Perlo J, Casanova F, Blümich B
Institut für Technische und Macromolekulare Chemie, RWTH Aachen D-52056, Germany.
J Magn Reson. 2004 Feb;166(2):228-35. doi: 10.1016/j.jmr.2003.10.018.
An open tomograph to image volume regions near the surface of large objects is described. The central achievement in getting such a tomograph to work is the design of a fast two-dimensional pure phase encoding imaging method to produce a cross-sectional image in the presence of highly inhomogeneous fields. The method takes advantage of the multi-echo acquisition in a Carr-Purcell-Meiboom-Gill (CPMG)-like sequence to significantly reduce the experimental time to obtain a 2D image or to spatially resolve relaxation times across the sensitive volume in a single imaging experiment. Depending on T(2) the imaging time can be reduced by a factor of up to two orders of magnitude compared to the one needed by the single-echo imaging technique. The complete echo train decay has been also used to produce T(2) contrast in the images and to spatially resolve the T(2) distribution of an inhomogeneous object, showing that variations of structural properties like the cross-link density of rubber samples can be distinguished by this method. The sequence has been implemented on a single-sided sensor equipped with an optimized magnet geometry and a suitable gradient coil system that provides two perpendicular pulsed gradient fields. The static magnetic field defines flat planes of constant frequency parallel to the surface of the scanner that can be selected by retuning the probe frequency to achieve slice selection into the object. Combining the slice selection obtained under the presence of the static gradient of the open magnet with the two perpendicular pulsed gradient fields, 3D spatial resolution is obtained.
描述了一种用于对大型物体表面附近的体积区域进行成像的开放式断层扫描仪。使这种断层扫描仪工作的核心成果是设计了一种快速二维纯相位编码成像方法,以便在高度不均匀场的情况下生成横截面图像。该方法利用类似 Carr-Purcell-Meiboom-Gill(CPMG)序列中的多回波采集,显著减少获取二维图像的实验时间,或者在单次成像实验中在敏感体积内空间分辨弛豫时间。根据 T(2),与单回波成像技术所需时间相比,成像时间最多可减少两个数量级。完整的回波串衰减也已用于在图像中产生 T(2) 对比度,并在空间上分辨不均匀物体的 T(2) 分布,表明该方法可以区分结构特性的变化,如橡胶样品的交联密度。该序列已在配备优化磁体几何结构和合适梯度线圈系统的单面传感器上实现,该系统提供两个垂直的脉冲梯度场。静磁场定义了与扫描仪表面平行的恒定频率平面,可以通过重新调谐探头频率来选择这些平面,以实现对物体的切片选择。将在开放式磁体的静态梯度存在下获得的切片选择与两个垂直的脉冲梯度场相结合,可获得三维空间分辨率。