Mima Tatsuya, Oga Tatsuhide, Rothwell John, Satow Takeshi, Yamamoto Jun-ichi, Toma Keiichiro, Fukuyama Hidenao, Shibasaki Hiroshi, Nagamine Takashi
Human Brain Research Center, Kyoto University Graduate School of Medicine, Human and Brain Research Center, Kyoto 606-8507, Japan.
Neurosci Lett. 2004 Jan 23;355(1-2):85-8. doi: 10.1016/j.neulet.2003.10.045.
Several previous studies have shown that periods of changed sensory input can have after effects on the excitability of the corticospinal system. Here we test whether the parameters of peripheral stimulation conventionally used to treat pain with transcutaneous electrical nerve stimulation (TENS: 90 Hz) also have modulatory effects on the motor system. We measured the amplitude of motor evoked potentials (MEPs) elicited by the focal transcranial magnetic stimulation in the right abductor pollicis brevis and first dorsal interosseous muscles before and after 30 min TENS over the right thenar eminence. In addition, we evaluated tactile and 2-point discrimination thresholds at the same site. TENS transiently reduced MEPs and increased sensory thresholds. This suggests that short-term TENS might have an inhibitory effect on both the sensory and motor systems.
先前的多项研究表明，感觉输入变化的时期可能会对皮质脊髓系统的兴奋性产生后续影响。在此，我们测试了传统上用于经皮电刺激神经疗法（TENS：90赫兹）治疗疼痛的外周刺激参数是否也对运动系统具有调节作用。我们在右侧鱼际隆起处进行30分钟的TENS治疗前后，测量了右侧拇短展肌和第一背侧骨间肌中由局灶性经颅磁刺激诱发的运动诱发电位（MEP）的幅度。此外，我们评估了同一部位的触觉和两点辨别阈值。TENS使MEP短暂降低，并提高了感觉阈值。这表明短期TENS可能对感觉和运动系统均具有抑制作用。
