呋喃丹诱发的急性胰腺炎。
Carbofuran-induced acute pancreatitis.
作者信息
Rizos Evangelos, Liberopoulos Evangelos, Kosta Paraskevi, Efremidis Stavros, Elisaf Moses
机构信息
Department of Internal Medicine, School of Medicine, University of Ioannina, Ioannina, Greece.
出版信息
JOP. 2004 Jan;5(1):44-7.
CONTEXT
Carbamate insecticides are widely used in commercial agriculture and home gardening. A serious side effect of organophosphate and carbamate intoxication is the development of acute pancreatitis.
CASE REPORT
A 36-year-old Caucasian woman was admitted to our hospital with cholinergic crisis and pancreatitis soon after the ingestion of a carbamate insecticide (carbofuran). An abdominal CT scan disclosed pancreatic necrosis with intrapancreatic fluid collection, consistent with the development of a pancreatic pseudocyst in a subsequent CT scan. No predisposing factor for pancreatitis was evident. Pseudocholinesterase levels returned to normal 7 days later and the patient was discharged in good physical condition one month after admission.
DISCUSSION
Although acute pancreatitis is not infrequent after organophosphate intoxication, it is quite rare after carbamate ingestion and has not been previously reported after carbofuran intoxication.
背景
氨基甲酸酯类杀虫剂广泛应用于商业农业和家庭园艺。有机磷和氨基甲酸酯类中毒的一个严重副作用是急性胰腺炎的发生。
病例报告
一名36岁的白人女性在摄入氨基甲酸酯类杀虫剂（呋喃丹）后不久因胆碱能危象和胰腺炎入住我院。腹部CT扫描显示胰腺坏死并伴有胰内液体积聚，这与后续CT扫描中胰腺假性囊肿的形成一致。未发现胰腺炎的诱发因素。假胆碱酯酶水平在7天后恢复正常，患者入院1个月后身体状况良好出院。
讨论
虽然急性胰腺炎在有机磷中毒后并不罕见，但在摄入氨基甲酸酯类后相当罕见，且此前呋喃丹中毒后未见报道。
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