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Exceptional increase in somatostatin receptor expression in pancreatic neuroendocrine tumour, visualised with (68)Ga-DOTATOC PET.

作者信息

Henze Marcus, Schuhmacher Jochen, Dimitrakopoulou-Strauss Antonia, Strauss Ludwig G, Mäcke Helmut R, Eisenhut Michael, Haberkorn Uwe

机构信息

Clinical Cooperation Unit, Nuclear Medicine, German Cancer Research Center, Heidelberg, Germany.

出版信息

Eur J Nucl Med Mol Imaging. 2004 Mar;31(3):466. doi: 10.1007/s00259-003-1436-2. Epub 2004 Jan 17.

DOI:10.1007/s00259-003-1436-2
PMID:14730407
Abstract
摘要

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Exceptional increase in somatostatin receptor expression in pancreatic neuroendocrine tumour, visualised with (68)Ga-DOTATOC PET.用（68）Ga-DOTATOC PET显像发现胰腺神经内分泌肿瘤中生长抑素受体表达异常增加。
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Should we stop offering indium-111 octreotide scans in favour of gallium-68 PET-CT scans in the UK?在英国，我们是否应该停止提供铟-111奥曲肽扫描，转而采用镓-68正电子发射断层扫描-计算机断层扫描（PET-CT）？
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引用本文的文献

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Radiolabeled cyclic RGD peptides as integrin alpha(v)beta(3)-targeted radiotracers: maximizing binding affinity via bivalency.放射性标记的环状 RGD 肽作为整合素 α(v)β(3)靶向放射性示踪剂：通过双价作用最大化结合亲和力。

本文引用的文献

1
Evaluation of positron emission tomography imaging using [68Ga]-DOTA-D Phe(1)-Tyr(3)-Octreotide in comparison to [111In]-DTPAOC SPECT. First results in patients with neuroendocrine tumors.使用[68Ga]-DOTA-D Phe(1)-Tyr(3)-奥曲肽的正电子发射断层扫描成像与[111In]-DTPA-奥曲肽单光子发射计算机断层扫描的比较评估。神经内分泌肿瘤患者的初步结果。
Mol Imaging Biol. 2003 Jan-Feb;5(1):42-8. doi: 10.1016/s1536-1632(03)00038-6.
2
Biokinetics and imaging with the somatostatin receptor PET radioligand (68)Ga-DOTATOC: preliminary data.生长抑素受体PET放射性配体（68）Ga-DOTATOC的生物动力学与成像：初步数据
Eur J Nucl Med. 2001 Dec;28(12):1751-7. doi: 10.1007/s002590100639. Epub 2001 Oct 31.
3
Bioconjug Chem. 2009 Dec;20(12):2199-213. doi: 10.1021/bc900167c.
4
Synthesis and biodistribution of lipophilic and monocationic gallium radiopharmaceuticals derived from N,N'-bis(3-aminopropyl)-N,N'-dimethylethylenediamine: potential agents for PET myocardial imaging with 68Ga.源自N,N'-双(3-氨丙基)-N,N'-二甲基乙二胺的亲脂性单阳离子镓放射性药物的合成与生物分布：用68Ga进行PET心肌成像的潜在药物。
Nucl Med Biol. 2009 Jan;36(1):39-45. doi: 10.1016/j.nucmedbio.2008.10.010.
5
Are radiogallium-labelled DOTA-conjugated somatostatin analogues superior to those labelled with other radiometals?放射性镓标记的DOTA偶联生长抑素类似物是否优于其他放射性金属标记的同类物？
Eur J Nucl Med Mol Imaging. 2007 Jul;34(7):982-93. doi: 10.1007/s00259-006-0317-x. Epub 2007 Jan 16.
PET imaging of somatostatin receptors using [68GA]DOTA-D-Phe1-Tyr3-octreotide: first results in patients with meningiomas.
使用[68GA]DOTA-D-苯丙氨酸1-酪氨酸3-奥曲肽对生长抑素受体进行PET成像：脑膜瘤患者的初步结果
J Nucl Med. 2001 Jul;42(7):1053-6.