Levine Mark
Department of Medicine, Buffett Taylor Chair in Breast Cancer Research, McMaster University, Canada.
Semin Thromb Hemost. 2003 Dec;29 Suppl 1:9-11. doi: 10.1055/s-2003-45410.
Thrombosis in the cancer patient is a unique problem. Cancer patients with acute venous thromboembolism are at increased risk of its recurrence compared with noncancer patients. Cancer patients are also at increased risk of anticoagulant-associated bleeding compared with noncancer patients. Finally, many cancer patients have a compromised quality of life and recurrent thrombosis has an additional negative impact on them. In order to optimize treatment of acute venous thromboembolism in cancer patients, the following outcomes must be considered: a reduction in the rate of recurrent venous thromboembolism, a reduction in the risk of bleeding compared to that seen with current anticoagulant treatment regimens, and a positive impact on the quality of life of the patient.
癌症患者的血栓形成是一个独特的问题。与非癌症患者相比，患有急性静脉血栓栓塞的癌症患者复发风险更高。与非癌症患者相比，癌症患者发生抗凝相关出血的风险也更高。最后，许多癌症患者的生活质量受到影响，而复发性血栓形成对他们有额外的负面影响。为了优化癌症患者急性静脉血栓栓塞的治疗，必须考虑以下结果：降低复发性静脉血栓栓塞的发生率，降低与当前抗凝治疗方案相比的出血风险，以及对患者生活质量产生积极影响。
