膜运输中的膜联蛋白。

Annexins in membrane traffic.

作者信息

Gruenberg J, Emans N

机构信息

European Molecular Biology Laboratory, Meyerhofstrasse 1, D-6900 Heidelberg, Germany.

出版信息

Trends Cell Biol. 1993 Jul;3(7):224-7. doi: 10.1016/0962-8924(93)90116-i.

DOI:10.1016/0962-8924(93)90116-i

PMID:14731757

Abstract

Annexins have long been though to be involved in exocytosis, possibly by helping to create close interactions between membranes destined to undergo fusion. In this article, we examine recent observations that implicate annexins in three different steps of the endocytic pathway, suggesting that annexins may be universal modulators of membrane trafficking.

摘要

长期以来，人们一直认为膜联蛋白参与胞吐作用，可能是通过帮助在注定要发生融合的膜之间建立紧密相互作用来实现的。在本文中，我们研究了最近的观察结果，这些结果表明膜联蛋白在内吞途径的三个不同步骤中发挥作用，这表明膜联蛋白可能是膜运输的通用调节剂。