微管成束研究再探讨：微管相关蛋白起作用吗？
Microtubule-bundling studies revisited: is there a role for MAPs?
作者信息
Lee G, Brandt R
机构信息
Center for Neurologic Diseases, Brigham and Women's Hospital, Program in Neurosciences, Harvard Medical School, Boston, MA 02115, USA.
出版信息
Trends Cell Biol. 1992 Oct;2(10):286-9. doi: 10.1016/0962-8924(92)90106-w.
The molecular mechanism of microtubule bundling has been enveloped in controversy for the past few years. At the centre of the debate are MAPs: are they necessary for the formation of microtubule bundles? In this article, Gloria Lee and Roland Brandt weigh the evidence and propose that microtubule stability might be the crucial factor in microtubule bundling. Perhaps then MAPs might act as spacer molecules between microtubules.
在过去几年里，微管成束的分子机制一直存在争议。争论的核心是微管相关蛋白（MAPs）：它们对于微管束的形成是必需的吗？在本文中，格洛丽亚·李和罗兰·勃兰特权衡了相关证据，并提出微管稳定性可能是微管成束的关键因素。那么，微管相关蛋白或许可能充当微管之间的间隔分子。
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