Chen L Z
Department of Pathology, The General Hospital of PLA, Beijing.
Zhonghua Bing Li Xue Za Zhi. 1992 Aug;21(4):229-31.
Three hundred and twenty-one biopsies from vulva, comprising 18 cases of condyloma acuminata (5.6%), 202 cases of pseudo-condyloma (62.9%), and 101 cases of non-specific vulvitis (31.5%), are reported. Clinically, most condylomata acuminata appeared as multiple soft papillary and verrucous lesions with local itchiness. The majority of patients with pseudo-condyloma were symptomless but with harbor roe-like warty papulae distributed symmetrically on both labia minora. Histologically, 18 cases of condyloma acuminata presented papillomatosis, parakeratosis, dyskeratosis, acanthosis, basal cell atypical hyperplasia and distinct koilocytosis. Pseudo-condylomata showed papillomatous growth but without atypical hyperplasia of basal cells and distinct koilocytosis.
报道了321例来自外阴的活检病例，其中包括18例尖锐湿疣（5.6%）、202例假性湿疣（62.9%）和101例非特异性外阴炎（31.5%）。临床上，大多数尖锐湿疣表现为多发性柔软乳头样和疣状病变，伴有局部瘙痒。大多数假性湿疣患者无症状，但有鱼子样疣状丘疹对称分布于双侧小阴唇。组织学上，18例尖锐湿疣表现为乳头瘤病、角化不全、角化不良、棘层肥厚、基底细胞非典型增生和明显的挖空细胞。假性湿疣表现为乳头样生长，但无基底细胞非典型增生和明显的挖空细胞。
