Sibley L D
Dept of Molecular Microbiology, Washington University School of Medicine, St Louis, MO 63110, USA.
Trends Cell Biol. 1995 Mar;5(3):129-32. doi: 10.1016/s0962-8924(00)88964-3.
Toxoplasma gondii actively invades its host cell rather than entering by conventional phagocytosis. Invasion is powered by a microfilament-based motility system in the parasite that leads to invagination of the host cell plasma membrane to form a novel intracellular vacuole. This vacuole resists fusion with the endocytic network of the host cell and provides a protective environment for replication of the parasite.
刚地弓形虫会主动侵入宿主细胞，而非通过传统的吞噬作用进入。寄生虫中基于微丝的运动系统驱动着入侵过程，该系统会导致宿主细胞质膜内陷，形成一个新的细胞内液泡。这个液泡能抵抗与宿主细胞内吞网络的融合，并为寄生虫的复制提供一个保护环境。
