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原发性HIV感染

Primary HIV Infection.

作者信息

Hare C. Bradley, Kahn James O.

机构信息

University of California, 3180 18th Street, Suite 305, San Francisco, CA 94110, USA.

出版信息

Curr Infect Dis Rep. 2004 Feb;6(1):65-71. doi: 10.1007/s11908-004-0026-1.

DOI:10.1007/s11908-004-0026-1
PMID:14733851
Abstract

Primary HIV infection is a critical and highly dynamic time period in the course of HIV infection. The initial pathologic processes are important in determining long-term disease progression. In the absence of our ability to eradicate the virus, identifying individuals during primary HIV infection and performing interventions that optimize outcome are important to provide adequate care to a newly infected patient and, from a public health perspective, to identify sexual networks and provide a platform to reduce HIV exposures during a time of high viremia.

摘要

原发性HIV感染是HIV感染过程中的一个关键且高度动态的时期。初始病理过程对于确定疾病的长期进展至关重要。在我们尚无根除病毒能力的情况下,在原发性HIV感染期间识别个体并进行优化治疗结果的干预措施,对于为新感染患者提供充分的治疗,以及从公共卫生角度识别性网络并提供一个在病毒血症高发期减少HIV暴露的平台而言都很重要。

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2
Antiretroviral drug resistance testing in adults infected with human immunodeficiency virus type 1: 2003 recommendations of an International AIDS Society-USA Panel.1型人类免疫缺陷病毒感染成人的抗逆转录病毒药物耐药性检测:美国国际艾滋病学会专家组2003年建议
Clin Infect Dis. 2003 Jul 1;37(1):113-28. doi: 10.1086/375597. Epub 2003 Jun 23.
3
Infect Dis Clin North Am. 2007 Jun;21(2):449-69, vii. doi: 10.1016/j.idc.2007.03.001.
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4
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