Dong Y Q
Beijing Army General Hospital of People's Liberation Army.
Zhonghua Wai Ke Za Zhi. 1992 Mar;30(3):180-3, 191.
Pulsed electric field was used on 22 dogs with incomplete spinal cord injury for 8-10 weeks. Nerve cells, nerve fibres and astrocytes were identified by monoclonal antibody to neurofilament or glial fibrillary acidic protein. Morphometric analysis was used for axon counting and GFAP area ratio calculation. The result indicated that there were more axons in the treated group than in the control group at the distal part of injured site. The cellular distribution and patterns of the active and stable phases may be a pathological recovering mark of the injured spinal cord. We conclude that the pulsed electric field may promote sprouting and elongating of the regenerative nerve fibres and may also have some modulating effects on the interaction of growth cones and astrocytes. The pulsed electric field may be superior to the direct current field in some aspects.
对22只脊髓不完全损伤的犬施加脉冲电场，持续8 - 10周。通过神经丝或胶质纤维酸性蛋白单克隆抗体鉴定神经细胞、神经纤维和星形胶质细胞。采用形态计量分析进行轴突计数和GFAP面积比计算。结果表明，治疗组损伤部位远端的轴突比对照组多。活跃期和稳定期的细胞分布及模式可能是脊髓损伤病理恢复的标志。我们得出结论，脉冲电场可能促进再生神经纤维的发芽和伸长，并且可能对生长锥与星形胶质细胞的相互作用也有一些调节作用。脉冲电场在某些方面可能优于直流电场。
