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[非创伤性脊柱硬膜外血肿。20例报告。文献综述及预后分析]

[Non traumatic spinal epidural hematomas. Report of twenty cases. Review of the literature and outcome aspects].

作者信息

Nuti C, Fotso M-J, Duthel R, Hatem O, Dumas B, Brunon J

机构信息

Service de Neurochirurgie, Hôpital Bellevue, CHU de Saint-Etienne, boulevard Pasteur, 42055 Saint-Etienne Cedex 2.

出版信息

Neurochirurgie. 2003 Dec;49(6):563-70.

Abstract

BACKGROUND AND PURPOSE

We report a personal series of 20 non traumatic spinal epidural hematomas and study outcome aspects with a review of data in the literature.

METHOD

Clinical presentation of non-traumatic spinal epidural hematomas observed between January 1980 and December 1998 was acute in 17 cases (85%) and chronic in 3 (15%). Symptoms were spinal and/or radicular pain, sensorimotor and sphincter dysfunction. Radiological evaluation consisted in myelography (n=6), myelography-CT scan (n=5), CT scan (n=1) and MRI (n=9). Patients underwent surgery in 15 cases, between 8 hours and 2 months after the first symptoms. All our patients were clinically reevaluated between 2 and 4 months after either surgery or admission for cases of spontaneous resolution.

RESULTS

Good results (complete neurological resolution or moderate sequelae) were observed in 14 patients (70%). A partial recovery with major persistent neurological impairment was observed in 1 patient (5%), an initial persistent neurological impairment in 1 (5%). Three patients (15%) died and 1 (5%) was lost to follow-up. Complete spontaneous resolution were observed in four patients.

CONCLUSION

Postsurgical outcome is mainly related to the preoperative neurological impairment, the duration of spinal cord compression and the time interval between the onset of symptoms and maximal deficit. A prompt laminectomy is necessary except in the cases where a spontaneous resolution can be expected from the early neurological course.

摘要

背景与目的

我们报告了一组20例非创伤性脊髓硬膜外血肿的病例,并结合文献数据对其预后情况进行研究。

方法

1980年1月至1998年12月期间观察到的非创伤性脊髓硬膜外血肿的临床表现,17例(85%)为急性,3例(15%)为慢性。症状包括脊髓和/或神经根性疼痛、感觉运动及括约肌功能障碍。影像学评估包括脊髓造影(n = 6)、脊髓造影 - CT扫描(n = 5)、CT扫描(n = 1)和MRI(n = 9)。15例患者在出现首发症状后的8小时至2个月内接受了手术。所有患者在术后2至4个月或对于自行缓解的病例在入院后2至4个月进行了临床复查。

结果

14例患者(70%)取得了良好的结果(神经功能完全恢复或遗留中度后遗症)。1例患者(5%)部分恢复但仍有严重的持续性神经功能损害,1例患者(5%)最初存在持续性神经功能损害。3例患者(15%)死亡,1例患者(5%)失访。4例患者出现了完全自行缓解。

结论

术后预后主要与术前神经功能损害、脊髓受压持续时间以及症状出现至最大神经功能缺损之间的时间间隔有关。除了从早期神经病程可预期自行缓解的病例外,及时进行椎板切除术是必要的。

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