通过基于途径选择性表型的筛选鉴定有效的Ras信号抑制剂。 - Suppr

Identification of potent Ras signaling inhibitors by pathway-selective phenotype-based screening.

作者信息

Müller Oliver, Gourzoulidou Eleni, Carpintero Mercedes, Karaguni Ioanna-Maria, Langerak Anette, Herrmann Christian, Möröy Tarik, Klein-Hitpass Ludger, Waldmann Herbert

机构信息

Max-Planck-Institut für molekulare Physiologie, Abteilung Strukturelle Biologie, Dortmund, Germany.

出版信息

Angew Chem Int Ed Engl. 2004 Jan 16;43(4):450-4. doi: 10.1002/anie.200352587.

DOI:10.1002/anie.200352587

PMID:14735532

Abstract

摘要

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Identification of potent Ras signaling inhibitors by pathway-selective phenotype-based screening.

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Identification of potent Ras signaling inhibitors by pathway-selective phenotype-based screening.

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Identification of potent Ras signaling inhibitors by pathway-selective phenotype-based screening.

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