Pawińska M, Skrzydlewska E
Department of Conservative Dentistry, Medical University of Białystok, ul. M. Skłodowskiej-Curie 24 A 15-276 Białystok, Poland.
Rocz Akad Med Bialymst. 2003;48:145-9.
The purpose of our study was to compare the in vitro release of hydroxyl ions from several calcium hydroxide preparations used in endodontic treatment.
Equal quantities of the materials--nonsetting (pure calcium hydroxide, Biopulp, Calcicure), setting--canal sealers (Sealapex, Apexit) and points were placed in dialysis tubes which were then immersed in deionized water. The release of hydroxyl ions from the preparations was measured by the median pH of the deionized water used for dialysis, by means of a pH-meter. The results of our study were analyzed by means of Tukey's reasonable correlation. Significance difference (one-way variance analysis ANOVA) and Pearson's linear correlation coefficient (r2).
Nonsetting preparations of calcium hydroxide have a significantly higher capability of hydroxyl ions release in comparison with sealers and points, irrespective of time (p < 0.05). Sealapex and "plus" points released hydroxyl ions to a much greater extent than both Apexit and "regular" points at most periods of the experiment (p < 0.05). Apexit released significantly more of hydroxyl ions than "regular" points, and Sealapex more than "plus" points in the later periods of the experiment (p < 0.05). The pH values of dialysis samples of all materials correlated positively with time and the pH. Almost all materials reached a maximum on the 8-th day of the experiment.
To achieve maximum concentration of hydroxyl ions in tissues: for temporary root fillings nonsetting preparations of calcium hydroxide should be chosen rather than points and they should be placed for at least one week, for permanent root fillings it is more recommended to use Sealapex than Apexit as a sealer.
本研究的目的是比较几种用于牙髓治疗的氢氧化钙制剂在体外释放氢氧根离子的情况。
将等量的材料——非凝固型（纯氢氧化钙、生物纸浆、钙化糊剂）、凝固型——根管封闭剂（Sealapex、Apexit）和牙胶尖置于透析管中，然后将透析管浸入去离子水中。通过用于透析的去离子水的中位pH值，借助pH计测量制剂中氢氧根离子的释放量。本研究结果采用Tukey合理相关性分析、显著性差异（单因素方差分析ANOVA）和Pearson线性相关系数（r2）进行分析。
无论时间如何，氢氧化钙的非凝固型制剂与封闭剂和牙胶尖相比，具有显著更高的氢氧根离子释放能力（p < 0.05）。在实验的大多数时间段内，Sealapex和“加”号牙胶尖释放氢氧根离子的程度比Apexit和“普通”牙胶尖大得多（p < 0.05）。在实验后期，Apexit释放的氢氧根离子明显多于“普通”牙胶尖，Sealapex释放的氢氧根离子多于“加”号牙胶尖（p < 0.05）。所有材料的透析样品的pH值与时间和pH呈正相关。几乎所有材料在实验的第8天达到最大值。
为了在组织中达到最大浓度的氢氧根离子：对于临时根管充填，应选择氢氧化钙的非凝固型制剂而非牙胶尖，并且应放置至少一周；对于永久根管充填，更推荐使用Sealapex而非Apexit作为封闭剂。
