Tavathia S, Rangayyan R M, Frank C B, Bell G D, Ladly K O, Zhang Y T
Department of Electrical and Computer Engineering, University of Calgary, Alta., Canada.
IEEE Trans Biomed Eng. 1992 Sep;39(9):959-70. doi: 10.1109/10.256430.
Clinical methods used at present for the diagnosis of cartilage pathology in the knee are invasive in nature, and carry some risks. There exists a need for the development of a safe, objective, noninvasive method for early detection, localization, and quantification of cartilage pathology in the knee. This paper investigates the possibility of developing such a method based on an analysis of vibrations produced by joint surfaces rubbing against one another during normal movement. In particular, the method of modeling by linear prediction is used for adaptive segmentation and parameterization of knee vibration signals. Dominant poles are extracted from the model system function for each segment based on their energy contributions and bandwidths. These dominant poles represent the dominant features of the signal segments in the spectral domain. Two-dimensional feature vectors are then constructed using the first dominant pole and the ratio of power in the 40-120 Hz band to the total power of the segment. The potential use of this method to distinguish between vibrations produced by normal volunteers and patients known to have cartilage pathology (chondromalacia) is discussed.
目前用于诊断膝关节软骨病变的临床方法本质上具有侵入性,且存在一定风险。因此,需要开发一种安全、客观、非侵入性的方法,用于早期检测、定位和量化膝关节软骨病变。本文基于对正常运动过程中关节面相互摩擦产生的振动进行分析,研究了开发这种方法的可能性。具体而言,采用线性预测建模方法对膝关节振动信号进行自适应分割和参数化。根据各段的能量贡献和带宽,从模型系统函数中提取主导极点。这些主导极点代表了信号段在频域中的主要特征。然后,利用第一个主导极点以及40 - 120 Hz频段功率与该段总功率的比值构建二维特征向量。本文还讨论了该方法区分正常志愿者和已知患有软骨病变(软骨软化症)患者所产生振动的潜在用途。