Farré Ramon
Unitat de Biofísica i Bioenginyeria, Facultat de Medicina, Universitat de Barcelona-IDIBAPS, Barcelona, Spain.
Clin Sci (Lond). 2004 Jun;106(6):563-5. doi: 10.1042/CS20040024.
Patients suffering from the obstructive sleep apnoea syndrome (OSAS) experience nocturnal episodes of upper airway obstruction resulting in recurrent oxygen desaturations and arousals. Methods to quantify the nocturnal obstructive events are of interest for characterizing this prevalent sleep disorder. In a study published in this issue of Clinical Science, Bloch and co-workers propose the computation of a new index for objectively quantifying the degree of flow limitation in patients with OSAS. The results obtained in a bench test and in a pilot study in patients suggest that the flow limitation index proposed may help to better characterize the disturbed breathing events undergone by patients with OSAS.
患有阻塞性睡眠呼吸暂停综合征(OSAS)的患者会经历夜间上呼吸道阻塞发作,导致反复的氧饱和度下降和觉醒。量化夜间阻塞性事件的方法对于表征这种常见的睡眠障碍很有意义。在本期《临床科学》发表的一项研究中,布洛赫及其同事提出计算一种新指标,用于客观量化OSAS患者的气流受限程度。在台架试验和患者的初步研究中获得的结果表明,所提出的气流受限指数可能有助于更好地表征OSAS患者所经历的呼吸紊乱事件。