Wilkins R, Janes S
Department of Haematology, St Richard's Hospital, Chichester, UK.
Clin Lab Haematol. 2004 Feb;26(1):73-5. doi: 10.1111/j.0141-9854.2003.00582.x.
'Aleukaemic leukaemia cutis' or acute leukaemia confined to the skin is extremely rare, although skin involvement with underlying leukaemia is well recognized, and is associated with a poor prognosis. We report a case of isolated acute myeloid leukaemia (AML) in the skin. A literature review shows this to be commonly misdiagnosed. Its recognition is important, because early diagnosis should lead to more appropriate chemotherapy, and a better prognosis. These patients probably require therapy directed specifically to the skin, as well as to other extramedullary sites, such as the central nervous system, to prevent early relapse.
“无白血病性白血病性皮肤病变”或局限于皮肤的急性白血病极为罕见，尽管白血病累及皮肤伴发潜在白血病已广为人知，且与预后不良相关。我们报告一例皮肤孤立性急性髓系白血病（AML）病例。文献综述显示该病常被误诊。认识到这一点很重要，因为早期诊断应能带来更合适的化疗方案，并改善预后。这些患者可能需要针对皮肤以及其他髓外部位（如中枢神经系统）的特异性治疗，以防止早期复发。
