Ciftçi Ergin, Ince Erdal, Doğru Ulker
Department of Paediatric Infectious Diseases, University of Ankara Medical School, Ankara, Turkey.
Ann Trop Paediatr. 2003 Dec;23(4):259-63. doi: 10.1179/027249303225007833.
Pyrexia of unknown origin (PUO) has not been appropriately investigated in Turkish children and therefore a study was undertaken to determine the causes of PUO and to evaluate which clinical procedures are useful in establishing a diagnosis. A total of 102 children fitting the classical PUO criteria seen in our clinic between 1995 and 2002 were investigated retrospectively. Infections, collagen vascular disorders, malignancy and miscellaneous conditions constituted 44.2%, 6.8%, 11.7% and 24.5% of cases, respectively, while 12.8% of the cases remained undiagnosed. Enteric fever, brucellosis and respiratory tract infections were the most commonly encountered infections, whereas familial Mediterranean fever was the commonest non-infectious disorder. Biopsy, aspiration, serology, bacteriology, radiology and observation of the clinical course were the most useful diagnostic procedures.
不明原因发热（PUO）在土耳其儿童中尚未得到充分研究，因此开展了一项研究以确定不明原因发热的病因，并评估哪些临床检查方法有助于确诊。回顾性调查了1995年至2002年间在我院就诊的符合经典不明原因发热标准的102例儿童。感染、胶原血管病、恶性肿瘤和其他病症分别占病例的44.2%、6.8%、11.7%和24.5%，而12.8%的病例仍未确诊。伤寒、布鲁氏菌病和呼吸道感染是最常见的感染，而家族性地中海热是最常见的非感染性疾病。活检、穿刺、血清学、细菌学、放射学检查以及临床病程观察是最有用的诊断方法。
