Urruticoechea A, Mesía R, Domínguez J, Falo C, Escalante E, Montes A, Sancho C, Cardenal F, Majem M, Germà J R
Medical Oncology Department, Institut Català d'Oncologia, Hospital Universitari de Bellvitge, L'Hospitalet, Barcelona, Spain.
Lung Cancer. 2004 Feb;43(2):209-14. doi: 10.1016/s0169-5002(03)00361-1.
Superior vena cava syndrome (SVCS) is a frequent presentation of malignancies involving the mediastinum and can seriously compromise treatment options and prognosis. Stenting of superior vena cava is a well-known but not so commonly used technique to alleviate this syndrome.
Between August 1993 and December 2000 we performed 52 stenting procedures in patients affected by non-small cell lung cancer (NSCLC).
Phlebographic resolution of the obstruction was achieved in 100% of cases with symptomatic and subjective improvement in more than 80%. One major complication was observed due to bleeding during anticoagulation. Re-obstruction of the stent occurred in only 17% of the cases, the majority due to disease progression. Improvement of the syndrome allowed hydration necessary for full dose platinum treatment when indicated in patients affected by lung cancer.
Stenting of the superior vena cava syndrome is a safe and effective procedure achieving a rapid alleviation of symptoms in almost all patients, and allowing for full dose treatment in lung cancer patients. This procedure could change the traditional poorer prognosis attributed to non-small cell lung cancer patients presenting with this syndrome.
上腔静脉综合征（SVCS）是纵隔恶性肿瘤的常见表现，会严重影响治疗方案和预后。上腔静脉支架置入术是一种缓解该综合征的知名但不太常用的技术。
1993年8月至2000年12月期间，我们对非小细胞肺癌（NSCLC）患者进行了52例支架置入手术。
100%的病例静脉造影显示梗阻得到缓解，超过80%的患者症状和主观感受有改善。观察到1例因抗凝期间出血导致的主要并发症。仅17%的病例出现支架再梗阻，多数是由于疾病进展。该综合征的改善使肺癌患者在需要时能够进行全剂量铂类治疗所需的水化。
上腔静脉综合征支架置入术是一种安全有效的手术，几乎能使所有患者症状迅速缓解，并能让肺癌患者接受全剂量治疗。该手术可能会改变传统上认为非小细胞肺癌患者出现此综合征时预后较差的情况。
