Castillo Monette S, Davis Faith G, Surawicz Tanya, Bruner Janet M, Bigner Sandra, Coons Stephen, Bigner Darell D
Department of Epidemiology/Biostatistics, University of Illinois at Chicago, School of Public Health, Chicago, IL 60612, USA.
Neuroepidemiology. 2004 Jan-Apr;23(1-2):85-93. doi: 10.1159/000073980.
High-quality cancer registry data are essential for assessing trends in incidence rates. This study evaluated the consistency of brain tumor surveillance data using a random sample of cases from the Connecticut Tumor Registry. Three neuropathologists independently and blindly reviewed tumor slides from 204 cases and a nosologist blindly reviewed and assigned International Classification of Diseases for Oncology (ICD-O) codes to 326 cases. For the pathology review, absolute concordance was as high as 81% for all primary brain tumors. Absolute concordance rates were high for nerve sheath (89%), meningioma (95%), and pituitary (95%) tumors. Rates were much lower for malignant tumors. ICD-O coding of malignant brain tumors is of relatively high quality with the exception of mixed gliomas and unspecified tumors. A high level of consistency for nonmalignant brain tumor diagnoses suggests that rates for these tumors, when actively reported to a surveillance system, can be of high quality.
高质量的癌症登记数据对于评估发病率趋势至关重要。本研究使用康涅狄格肿瘤登记处的病例随机样本评估了脑肿瘤监测数据的一致性。三位神经病理学家独立且盲法审查了204例病例的肿瘤切片，一位疾病分类学家盲法审查并为326例病例分配了国际肿瘤疾病分类（ICD-O）编码。对于病理审查，所有原发性脑肿瘤的绝对一致性高达81%。神经鞘瘤（89%）、脑膜瘤（95%）和垂体瘤（95%）的绝对一致性率很高。恶性肿瘤的一致性率则低得多。除混合性胶质瘤和未明确肿瘤外，恶性脑肿瘤的ICD-O编码质量相对较高。非恶性脑肿瘤诊断的高度一致性表明，当这些肿瘤被积极报告给监测系统时，其发病率数据可以具有较高质量。
