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使用覆膜金属支架缓解复发性胃癌吻合口梗阻:25例患者的临床结果

Palliation of anastomotic obstructions in recurrent gastric carcinoma with the use of covered metallic stents: clinical results in 25 patients.

作者信息

Jeong Jun Yong, Kim Young Jun, Han Joon Koo, Lee Jeong Min, Lee Kyoung Ho, Choi Byung Ihn, Yang Han-Kwang, Lee Kuhn Uk

机构信息

Department of Radiology, Seoul National University College of Medicine, Seoul, Korea.

出版信息

Surgery. 2004 Feb;135(2):171-7. doi: 10.1016/s0039-6060(03)00346-5.

Abstract

BACKGROUND

The purpose of this study was to investigate the technical feasibility and the clinical effectiveness of the placement of covered self-expandable metallic stents for the treatment of anastomotic obstructions in recurrent gastric carcinoma.

METHODS

With fluoroscopic guidance, covered stents were placed in 25 patients with recurrent gastric carcinoma for the palliation of obstructions at anastomotic sites (14 gastrojejunostomy, 11 esophagojejunostomy). All patients had severe nausea and recurrent vomiting before the stent placement.

RESULTS

Stent placement was technically successful in 24 patients (96%). After stent placement, symptoms improved in all 24 patients. During the follow-up of 2 to 65 weeks (mean, 13.7 weeks), stent migration occurred in 1 patient 16 days after the procedure. He needed percutaneous catheter drainage because of an abscess, which was followed by esophagojejunostomy site rupture during a second stent trial. Stricture recurred in 4 patients because of tumor overgrowth 10 to 55 weeks after the procedure; all patients underwent coaxial placement of a second stent and had good oral intake.

CONCLUSIONS

The placement of covered expandable metallic stents seems to be both technically feasible and an effective means for the palliation of anastomotic obstructions in recurrent gastric carcinoma. This procedure can be considered to be the primary choice for the palliation in those patients.

摘要

背景

本研究旨在探讨置入覆膜自膨式金属支架治疗复发性胃癌吻合口梗阻的技术可行性及临床疗效。

方法

在透视引导下,为25例复发性胃癌患者置入覆膜支架以缓解吻合口部位的梗阻(14例为胃空肠吻合口,11例为食管空肠吻合口)。所有患者在置入支架前均有严重恶心及反复呕吐症状。

结果

24例患者(96%)支架置入技术成功。置入支架后,所有24例患者症状均改善。在2至65周(平均13.7周)的随访期间,1例患者在术后16天发生支架移位。因脓肿形成,他需要经皮导管引流,随后在第二次尝试置入支架时食管空肠吻合口部位破裂。4例患者在术后10至55周因肿瘤过度生长导致狭窄复发;所有患者均接受了同轴置入第二个支架,且经口进食情况良好。

结论

置入覆膜可膨胀金属支架似乎在技术上可行,且是缓解复发性胃癌吻合口梗阻的有效手段。该方法可被视为这些患者姑息治疗的首选。

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