表没食子儿茶素没食子酸酯的氧化偶联增强抗氧化活性并抑制黄嘌呤氧化酶活性。
Oxidative coupling of epigallocatechin gallate amplifies antioxidant activity and inhibits xanthine oxidase activity.
作者信息
Kurisawa Motoichi, Chung Joo Eun, Uyama Hiroshi, Kobayashi Shiro
机构信息
Bio-oriented Technology Research Advancement Institution, and Department of Materials Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan.
出版信息
Chem Commun (Camb). 2004 Feb 7(3):294-5. doi: 10.1039/b312311a. Epub 2003 Dec 19.
DOI:10.1039/b312311a
PMID:14740044
Abstract
Oxidative coupling of epigallocatechin gallate resulted in great improvement in antioxidant activity such as radical scavenging activity against superoxide anion and in activity to inhibit xanthine oxidase, offering high potential as a therapeutic agent for prevention of xanthine oxidase-induced diseases such as gout.
摘要
表没食子儿茶素没食子酸酯的氧化偶联极大地提高了抗氧化活性，如对超氧阴离子的自由基清除活性以及抑制黄嘌呤氧化酶的活性，具有作为预防痛风等黄嘌呤氧化酶诱导疾病的治疗剂的巨大潜力。
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