Ellis R J, Born M, Feit T, Ebert P A
Department of Surgery, Veterans Administration Hospital, San Francisco, California 94121, USA.
Circulation. 1978 Sep;58(3 Pt 2):I57-61.
Left ventricular function was evaluated by single pass Tc-99m radionuclide ventriculography when potassium cardioplegia was combined with hypothermia. In 35 patients undergoing myocardial revascularization (3 CABG/patient) in which potassium cardioplegia at 4 degrees C was used, no patient developed a myocardial infarction either by electrocardiogram or Tc-99m pyrophosphate imaging in the postoperative period. In 22 patients, aortic cross-clamp time was greater than 60 min, and the ejection fraction by the single pass radionuclide technique was 50% preoperatively and 53% postoperatively (NS). Wall motion in the single RAO view was not worse postoperatively. No patient required any inotropic agents in the immediate postoperative period. It appears that no significant ventricular impairment occurred in the immediate postoperative period (48 to 72 hours) when potassium cardioplegia combined with hypothermia was used for a 60-minute period.
当钾停搏液与低温联合应用时，通过单次通过99m锝放射性核素心室造影评估左心室功能。在35例接受心肌血运重建术（每位患者行3次冠状动脉搭桥术）并使用4℃钾停搏液的患者中，术后无一例患者通过心电图或99m锝焦磷酸盐显像出现心肌梗死。在22例患者中，主动脉阻断时间超过60分钟，术前单次通过放射性核素技术测得的射血分数为50%，术后为53%（无统计学意义）。术后右前斜位单视图中的壁运动情况并未变差。术后即刻无一例患者需要使用任何正性肌力药物。当钾停搏液与低温联合应用60分钟时，术后即刻（48至72小时）似乎未发生明显的心室功能损害。
