Kawashima Ryuta, Taira Masato, Okita Katsuo, Inoue Kentaro, Tajima Nobumoto, Yoshida Hajime, Sasaki Takeo, Sugiura Motoaki, Watanabe Job, Fukuda Hiroshi
NICHe, Tohoku University, Sendai, 980-8579, Japan.
Brain Res Cogn Brain Res. 2004 Feb;18(3):227-33. doi: 10.1016/j.cogbrainres.2003.10.009.
The purpose of this study was to examine brain areas involved in simple arithmetic, and to compare these areas between adults and children. Eight children (four girls and four boys; age, 9-14 years) and eight adults (four women and four men; age, 40-49 years) were subjected to this study. Functional magnetic resonance imaging (fMRI) was performed during mental calculation of addition, subtraction, and multiplication of single digits. In each group, the left middle frontal, bilateral inferior temporal and bilateral lateral occipital cortices were activated during each task. The adult group showed activation of the right frontal cortex during addition and multiplication tasks, but the children group did not. Activation of the intraparietal cortex was observed in the adult group during each task. Although, activation patterns were slightly different among tasks, as well as between groups, only a small number of areas showed statistically significant differences. The results indicate that cortical networks involved in simple arithmetic are similar among arithmetic operations, and may not show significant changes in the structure during the second decade of life.
本研究的目的是检查参与简单算术的脑区，并比较成人和儿童之间的这些脑区。八名儿童（四名女孩和四名男孩；年龄9 - 14岁）和八名成人（四名女性和四名男性；年龄40 - 49岁）参与了本研究。在进行个位数加法、减法和乘法的心算过程中进行了功能磁共振成像（fMRI）。在每组中，每个任务期间左额中回、双侧颞下回和双侧枕外侧皮质均被激活。成人组在加法和乘法任务期间右侧额叶皮质被激活，但儿童组未出现这种情况。在成人组的每个任务期间均观察到顶内皮质的激活。尽管任务之间以及组间的激活模式略有不同，但只有少数脑区显示出统计学上的显著差异。结果表明，参与简单算术的皮质网络在算术运算之间相似，并且在生命的第二个十年期间结构可能不会出现显著变化。
