喉癌术后复发相关因素的临床分析
[Clinical analysis of relevant factors causing laryngeal cancer postoperative recurrence].
作者信息
Guo Rui, Huang De-liang, Li Hui, Yang Wei-yan, Han Dong-yi
机构信息
Department of Otorhinolaryngology, PLA General Hospital, Beijing 100853, China.
出版信息
Zhonghua Er Bi Yan Hou Ke Za Zhi. 2003 Aug;38(4):300-3.
OBJECTIVE
To investigate the clinical relevant factors causing laryngeal cancer postoperative recurrence and analysis the reasons of treatment failure.
METHODS
Totally, 574 cases of laryngeal cancer from 1958 to 1999 treated in ENT department of PLA general hospital were retrospectively reviewed. All the patients were observed for 3 years postoperatively, and finally 56 cases of the recurrence were diagnosed. We analyzed the factors possibly causing the recurrence including age, sex, history, time in hospital, smoke, grade of pathology, combination, tumor stage, transfusion, radiotherapy, operation manners and cervical lymph metastasis node grade.
RESULTS
By statistic analysis, tumor grade (P = 0.0002), operation (P = 0.0017), transfusion (P = 0.0001), radiotherapy (P = 0.0001) and cervical lymphatic metastasis node grade(P = 0.0228) have significant meaning with laryngeal cancer postoperative recurrence.
CONCLUSION
Tumor grade, transfusion, radiotherapy, operation and cervical lymph metastasis node grade are main factors which may cause neoplasm postoperative recurring.
目的
探讨喉癌术后复发的临床相关因素并分析治疗失败的原因。
方法
回顾性分析1958年至1999年解放军总医院耳鼻咽喉科收治的574例喉癌患者。所有患者术后观察3年，最终确诊复发56例。分析可能导致复发的因素，包括年龄、性别、病史、住院时间、吸烟、病理分级、联合治疗、肿瘤分期、输血、放疗、手术方式及颈部淋巴结转移分级。
结果
经统计学分析，肿瘤分级（P = 0.0002）、手术（P = 0.0017）、输血（P = 0.0001）、放疗（P = 0.0001）及颈部淋巴结转移分级（P = 0.0228）与喉癌术后复发有显著意义。
结论
肿瘤分级、输血、放疗、手术及颈部淋巴结转移分级是可能导致肿瘤术后复发的主要因素。
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