Smith Joseph R, King Don W, Park Yong D, Murro Anthony M, Lee Gregory P, Jenkins Patrick D
Department of Neurosurgery, Medical College of Georgia, Augusta, GA 30912, USA.
Stereotact Funct Neurosurg. 2003;80(1-4):14-7. doi: 10.1159/000075153.
Magnetic source imaging (MSI) of interictal epileptiform dipoles was studied in 100 epilepsy surgery candidates. Sixty underwent surgery. MSI epileptiform data were classified as focal, regional, multifocal, scattered or none. Resections of MSI epileptiform foci were classified as extensive (EXT) versus partial or none (P/N). MSI interictal epileptiform dipoles were found in 22 of 27 anterior temporal (ATL) cases, and in 31 of 33 extratemporal (XMT) cases. Of 10 EXT ATL cases, 5 (50%) were seizure free (SF). Of 12 P/N ATL cases, 7 (58%) were SF. Of 10 nonlesional EXT XMT resections, 8 (80%) were SF. Of 10 nonlesional P/N XMT resections, 1 (10%) was SF. Neither focality of MSI data or spatial agreement of electrographic and MSI data significantly affected outcomes.
对100名癫痫手术候选者进行了发作间期癫痫样偶极子的磁源成像（MSI）研究。其中60人接受了手术。MSI癫痫样数据被分类为局灶性、区域性、多灶性、散在性或无。MSI癫痫样病灶的切除被分类为广泛性（EXT）与部分性或无（P/N）。在27例前颞叶（ATL）病例中的22例以及33例颞叶外（XMT）病例中的31例发现了MSI发作间期癫痫样偶极子。在10例广泛性ATL病例中，5例（50%）无癫痫发作（SF）。在12例部分性或无ATL病例中，7例（58%）无癫痫发作。在10例非病变性广泛性XMT切除病例中，8例（80%）无癫痫发作。在10例非病变性部分性或无XMT切除病例中，1例（10%）无癫痫发作。MSI数据的局灶性或脑电图与MSI数据的空间一致性均未显著影响手术结果。
