Takahashi Satoru, Murakami Takamichi, Takamura Manabu, Kim Tonsok, Hori Masatoshi, Narumi Yoshifumi, Nakamura Hironobu
Department of Clinical Informative Imagiology, Osaka University Graduate School of Medicine, Osaka, Japan.
J Magn Reson Imaging. 2004 Feb;19(2):194-201. doi: 10.1002/jmri.10443.
To evaluate the usefulness of half-dose contrast-enhanced magnetic resonance (MR) angiography for depicting the abdominal aorta and its major branches.
A total of 72 consecutive patients were randomly assigned to one of four groups that underwent MR angiography after receiving different concentrations (original or diluted to 50%) and total amounts (single or half-dose) of gadolinium chelate injected at different rates (1 or 0.5 mL/second). The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of the abdominal aorta and of the common and external iliac arteries were calculated, and two blinded readers rated the respective image qualities.
The SNR and CNR of the abdominal aorta and the common iliac artery in the 0.5 mL/second groups were statistically significantly lower than those in the 1 mL/second groups. The differences in overall image quality across the four groups were not statistically significant.
Half-dose MR angiography using diluted contrast medium injected at a rate of 1 mL/second depicted the abdominal aorta and its branches as clearly as using a full single dose.
评估半剂量对比增强磁共振（MR）血管造影术在显示腹主动脉及其主要分支方面的效用。
连续72例患者被随机分为四组，在以不同速率（1或0.5 mL/秒）注射不同浓度（原液或稀释至50%）和总量（单剂量或半剂量）的钆螯合物后接受MR血管造影术。计算腹主动脉、髂总动脉和髂外动脉的信噪比（SNR）和对比噪声比（CNR），两位盲法阅片者对各自的图像质量进行评分。
0.5 mL/秒组腹主动脉和髂总动脉的SNR和CNR在统计学上显著低于1 mL/秒组。四组总体图像质量的差异无统计学意义。
以1 mL/秒的速率注射稀释对比剂的半剂量MR血管造影术显示腹主动脉及其分支的清晰度与使用全单剂量时相同。
