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瑞典年轻人的心源性猝死:与法医诊断相关的心电图

Sudden cardiac death in the young in Sweden: electrocardiogram in relation to forensic diagnosis.

作者信息

Wisten A, Andersson S, Forsberg H, Krantz P, Messner T

机构信息

Department of Internal Medicine, Sunderby Hospital, Luleå, Sweden.

出版信息

J Intern Med. 2004 Feb;255(2):213-20. doi: 10.1046/j.1365-2796.2003.01277.x.

DOI:10.1046/j.1365-2796.2003.01277.x
PMID:14746558
Abstract

OBJECTIVES

To study electrocardiogram (ECG) in relation to forensic diagnosis in young persons who suffered a sudden cardiac death (SCD) in Sweden during 1992-99.

DESIGN

A register study of a national database of forensic medicine in Sweden, selecting all cases of SCD 15-35 years of age. In this group, 12-lead ECGs and clinical data were searched for in military conscription and medical records. The ECGs were re-analysed and classified according to the Minnesota code criteria.

SETTING

The whole nation of Sweden.

SUBJECTS

Sudden cardiac death victims (66 individuals), 15-35 years of age, where it was possible to obtain an ECG recording.

RESULTS

We observed major or minor ECG abnormalities in 82% of the subjects. The most common changes were T wave abnormalities (35%), ST segment changes (32%) and conduction defects (20%). The ECGs were evaluated as pathological in 50% of the cases, more often in arrhythmogenic right ventricular cardiomyopathy (88%) and hypertrophic cardiomyopathy (82%). Cardiac-related symptoms were seen in 76% of the total group and there was a family history of a similar cardiac condition in 18%.

CONCLUSIONS

Pathological ECGs were common in young SCD victims, in spite of being taken many years before death. An ECG could help identify prospective victims of SCD, and should always be taken in cases with possible cardiac-related symptoms or a family history of SCD. The pathological ECGs were often found in connection with routine screening at military enlistment for men, which raises the question of a routine screening in the young, including women.

摘要

目的

研究1992 - 1999年期间在瑞典发生心脏性猝死(SCD)的年轻人的心电图(ECG)与法医诊断的关系。

设计

对瑞典国家法医学数据库进行登记研究,选取所有15 - 35岁的SCD病例。在该组中,在征兵记录和医疗记录中查找12导联心电图和临床数据。根据明尼苏达编码标准对心电图进行重新分析和分类。

地点

瑞典全国。

研究对象

15 - 35岁的心脏性猝死受害者(66人),有可能获得心电图记录。

结果

我们在82%的研究对象中观察到主要或轻微的心电图异常。最常见的变化是T波异常(35%)、ST段改变(32%)和传导缺陷(20%)。50%的病例心电图被评估为病理性,在致心律失常性右室心肌病(88%)和肥厚型心肌病(82%)中更常见。76%的总研究对象有心脏相关症状,18%有类似心脏疾病的家族史。

结论

病理性心电图在年轻的心脏性猝死受害者中很常见,尽管是在死亡前多年记录的。心电图有助于识别心脏性猝死的潜在受害者,对于有心脏相关症状或心脏性猝死家族史的病例应常规进行心电图检查。病理性心电图常在男性征兵常规筛查时发现,这引发了对年轻人包括女性进行常规筛查的问题。

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