Le Lay S, Ferré P, Dugail I
INSERM U 465, Institut Biomedical des Cordeliers, 15, rue de l'école de médecine, 75006 Paris, France.
Biochem Soc Trans. 2004 Feb;32(Pt 1):103-6. doi: 10.1042/bst0320103.
Adipose tissue is specialized in the storage of energy in the form of triacylglycerol. Within the fat cell, triacylglycerols are found in a well-defined structural compartment called the lipid droplet, which occupies the vast majority of the fat cell volume. However, many other lipids are present in the lipid droplet. These include sterols, carotenoids, cholecalciferol and lipophilic toxic pollutants of the environment such as dioxins and tocopherols. The topic of this article is the role of fat cell cholesterol in adipose tissue physiology and its potential implication in pathological states such as obesity.
脂肪组织专门以三酰甘油的形式储存能量。在脂肪细胞内，三酰甘油存在于一个定义明确的结构区室中，称为脂滴，它占据了脂肪细胞体积的绝大部分。然而，脂滴中还存在许多其他脂质。这些包括固醇、类胡萝卜素、胆钙化醇以及环境中的亲脂性有毒污染物，如二噁英和生育酚。本文的主题是脂肪细胞胆固醇在脂肪组织生理学中的作用及其在肥胖等病理状态中的潜在影响。
