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孕妇宫颈黏液中的早期妊娠因子。

Early pregnancy factor in cervical mucus of pregnant women.

作者信息

Cheng Shu-Juan, Zheng Zhen-Qun

机构信息

The Institute of Geriatric Cardiology, The General Hospital of Chinese PLA, Beijing 100853, China.

出版信息

Am J Reprod Immunol. 2004 Feb;51(2):102-5. doi: 10.1046/j.8755-8920.2003.00136.x.

Abstract

PROBLEM

This study was carried out to determine the presence of early pregnancy factor (EPF) activity in cervical mucus of pregnant women and explore the relationship between EPF activity in sera suggested it and in cervical mucus.

METHOD OF STUDY

Cervical mucus and sera were collected from 60 pregnant women in different terms and 25 non-pregnant women, respectively. EPF activity was detected by rosette inhibition assay.

RESULTS

EPF activity did exist in cervical mucus of pregnant women and was similar both in cervical mucus and sera.

CONCLUSIONS

We report here for the first time the EPF activity in cervical mucus of pregnant women. The parallel change observed in sera suggested it might be another useful index in evaluating embryo viability.

摘要

问题

本研究旨在确定孕妇宫颈黏液中早孕因子(EPF)活性的存在,并探讨血清与宫颈黏液中EPF活性之间的关系。

研究方法

分别收集了60例不同孕周孕妇和25例非孕妇的宫颈黏液及血清。采用玫瑰花环抑制试验检测EPF活性。

结果

孕妇宫颈黏液中确实存在EPF活性,且宫颈黏液与血清中的EPF活性相似。

结论

我们首次报道了孕妇宫颈黏液中的EPF活性。血清中观察到的平行变化表明,它可能是评估胚胎活力的另一个有用指标。

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