Speer Cornelia, Pelz Klaus, Hopfenmüller Werner, Holtgrave Eva-Andrea
Department of Orthodontics and Pediatric Dentistry, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.
J Orofac Orthop. 2004 Jan;65(1):34-47. doi: 10.1007/s00056-004-0333-z.
The aim of the present study was to investigate changes in the subgingival flora in adults with chronic periodontitis undergoing orthodontic fixed appliance therapy.
In seven adult patients who had undergone nonantibiotic periodontal pretreatment, the subgingival bacteria were subjected to microbiological examination and the number of periodontopathogenic organisms was determined before (T1: prior to treatment being started), during (T2: 6 weeks after orthodontic treatment was started) and after the end of orthodontic treatment (T3: 6 weeks after removal of the fixed appliances).
During the fixed appliance therapy (metal brackets, NiTi archwires, stainless steel archwires), a marked reduction was observed in the total bacteria count from the subgingival pocket despite the clinical periodontal parameters remaining almost unchanged. However, the total count of some highly pathogenic bacteria rose again slightly after the end of treatment. We attribute the marked improvement in the periodontopathogenic bacteria spectrum under fixed appliance therapy with metal brackets, NiTi archwires and stainless steel archwires to metal corrosion entailing the release of primarily nickel ions, which have a toxic effect on bacteria and thus enable the regeneration of the physiological bacterial flora. In none of the patients was a deterioration of the periodontal status observed during and after fixed appliance therapy.
本研究旨在调查接受正畸固定矫治器治疗的慢性牙周炎成年患者龈下菌群的变化。
对7例接受过非抗生素牙周预处理的成年患者，在正畸治疗开始前（T1）、正畸治疗开始后6周（T2）以及正畸治疗结束后6周（T3：去除固定矫治器后6周），对龈下细菌进行微生物学检查并确定牙周致病菌数量。
在固定矫治器治疗期间（金属托槽、镍钛弓丝、不锈钢弓丝），尽管临床牙周参数几乎保持不变，但龈下袋内细菌总数显著减少。然而，治疗结束后一些高致病性细菌的总数略有回升。我们将使用金属托槽、镍钛弓丝和不锈钢弓丝进行固定矫治器治疗期间牙周致病菌谱的显著改善归因于金属腐蚀导致主要镍离子的释放，镍离子对细菌具有毒性作用，从而使生理性细菌菌群得以再生。在固定矫治器治疗期间及治疗后，未观察到任何患者的牙周状况恶化。
