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High-efficiency gene transfer into cardiac myocytes.

作者信息

Xu H, Miller J, Liang B T

机构信息

Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia 19104.

出版信息

Nucleic Acids Res. 1992 Dec 11;20(23):6425-6. doi: 10.1093/nar/20.23.6425.

DOI:10.1093/nar/20.23.6425
PMID:1475211
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC334546/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58fe/334546/d34c69e6af59/nar00234-0279-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58fe/334546/d34c69e6af59/nar00234-0279-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58fe/334546/d34c69e6af59/nar00234-0279-a.jpg

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Cell-specific expression of the rat insulin gene: evidence for role of two distinct 5' flanking elements.大鼠胰岛素基因的细胞特异性表达:两个不同的5'侧翼元件作用的证据。
Science. 1985 Nov 22;230(4728):912-6. doi: 10.1126/science.3904002.
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Differential sensitivity of alpha o and alpha i to ADP-ribosylation by pertussis toxin in the intact cultured embryonic chick ventricular myocyte. Relationship to the role of G proteins in the coupling of muscarinic cholinergic receptors to inhibition of adenylate cyclase activity.完整培养的胚胎鸡心室肌细胞中αo和αi对百日咳毒素ADP-核糖基化的差异敏感性。与G蛋白在毒蕈碱胆碱能受体与腺苷酸环化酶活性抑制偶联中的作用的关系。
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腺苷通过受体亚型与磷脂酶C和D的差异偶联介导的独特心脏保护作用。
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Cardiac myocytes rendered ischemia resistant by expressing the human adenosine A1 or A3 receptor.通过表达人腺苷A1或A3受体而具有抗缺血能力的心肌细胞。
FASEB J. 1998 Dec;12(15):1785-92. doi: 10.1096/fasebj.12.15.1785.
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A physiological role of the adenosine A3 receptor: sustained cardioprotection.腺苷A3受体的生理作用:持续的心脏保护作用。
Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):6995-9. doi: 10.1073/pnas.95.12.6995.
6
Enhanced expression of p53 and apoptosis induced by blockade of the vacuolar proton ATPase in cardiomyocytes.心肌细胞中液泡质子ATP酶阻断诱导的p53表达增强及细胞凋亡
J Clin Invest. 1998 Mar 15;101(6):1453-61. doi: 10.1172/JCI345.
7
Induction of the cholesterol metabolic pathway regulates the farnesylation of RAS in embryonic chick heart cells: a new role for ras in regulating the expression of muscarinic receptors and G proteins.胆固醇代谢途径的诱导调节胚胎鸡心脏细胞中RAS的法尼基化:RAS在调节毒蕈碱受体和G蛋白表达中的新作用。
EMBO J. 1997 Dec 15;16(24):7250-60. doi: 10.1093/emboj/16.24.7250.
8
p53 and the hypoxia-induced apoptosis of cultured neonatal rat cardiac myocytes.p53与培养的新生大鼠心肌细胞缺氧诱导的凋亡
J Clin Invest. 1997 Jun 1;99(11):2635-43. doi: 10.1172/JCI119452.
9
Direct preconditioning of cultured chick ventricular myocytes. Novel functions of cardiac adenosine A2a and A3 receptors.培养的鸡心室肌细胞的直接预处理。心脏腺苷A2a和A3受体的新功能。
J Clin Invest. 1996 Oct 15;98(8):1773-9. doi: 10.1172/JCI118976.
10
A novel method of identifying living transfected cardiac myocyte.一种鉴定存活的转染心肌细胞的新方法。
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GAL4 activates transcription in Drosophila.GAL4在果蝇中激活转录。
Nature. 1988 Apr 28;332(6167):853-6. doi: 10.1038/332853a0.
4
Single cell analysis of transfected gene expression in primary heart cultures containing multiple cell types.对含有多种细胞类型的原代心脏培养物中转染基因表达的单细胞分析。
Biotechniques. 1988 Jul-Aug;6(7):640-2, 645-9.
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Mechanisms of beta-adrenergic receptor regulation in cultured chick heart cells. Role of cytoskeleton function and protein synthesis.培养的鸡心脏细胞中β-肾上腺素能受体的调节机制。细胞骨架功能和蛋白质合成的作用。
Circ Res. 1985 Jul;57(1):171-81. doi: 10.1161/01.res.57.1.171.
6
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