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Developmental biology. A pattern of precision.

作者信息

Sternberg Paul W

机构信息

Howard Hughes Medical Institute and Division of Biology 156-29, California Institute of Technology, Pasadena, CA 91125, USA.

出版信息

Science. 2004 Jan 30;303(5658):637-8. doi: 10.1126/science.1094409.

DOI:10.1126/science.1094409
PMID:14752152
Abstract
摘要

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Developmental biology. A pattern of precision.发育生物学。一种精确模式。
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lin-17/Frizzled and lin-18 regulate POP-1/TCF-1 localization and cell type specification during C. elegans vulval development.lin-17/卷曲蛋白和lin-18在秀丽隐杆线虫外阴发育过程中调节POP-1/TCF-1的定位和细胞类型特化。
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Developmental fidelity is imposed by genetically separable RalGEF activities that mediate opposing signals.发育保真度受遗传上可分离的 RalGEF 活性的限制,这些活性介导相反的信号。
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