Hedman Anders, Alam Mahbubul, Zuber Ernst, Nordlander Rolf, Samad Bassem Abdel
Department of Cardiology, Karolinska Institute at Söder Hospital (Södersjukhuset), S-11883 Stockholm, Sweden.
J Am Soc Echocardiogr. 2004 Feb;17(2):126-31. doi: 10.1016/j.echo.2003.10.023.
Decreased right ventricular (RV) function is a known echocardiographic finding after coronary artery bypass grafting (CABG). For patients with heart failure, RV dysfunction is a predictor of poor exercise capacity. The significance and time course of RV dysfunction and its relation to exercise capacity after CABG have not been elucidated, however.
In this prospective study, we assessed RV function measured from echocardiographic tricuspid annular motion (TAM) before and after CABG and its relation to exercise capacity.
In 99 patients accepted for CABG, we did a baseline echocardiographic investigation before operation, followed by repeated echocardiograms 3 months and 1 year after CABG. RV function was assessed using the magnitude of TAM measured at the RV free wall. An exercise stress test and coronary angiography were performed before and 3 months after CABG.
RV function assessed by TAM was significantly reduced 3 months after CABG (22.4 vs 14.5 mm, P <.001) compared with preoperative measurements and remained so after 1 year (14.7 mm, P <.001). Left ventricular systolic function was unchanged 3 months after CABG. The 1-year echocardiographic follow-up showed paradoxical septal movement in 96% of the patients. Exercise capacity improved significantly 3 months after CABG compared with before (1.6 vs 1.83 W/kg, P <.001). These finding are independent of the state of the right coronary artery.
One year after CABG, RV function remained depressed and septal motion remained paradoxical compared with the preoperative investigation, suggesting that these postoperative findings might be permanent in the majority of patients. Despite the reduced RV function, exercise performance 3 months after CABG was improved. The depressed RV function, measured from TAM after CABG, probably lacks clinical significance.
右心室(RV)功能降低是冠状动脉旁路移植术(CABG)后已知的超声心动图表现。对于心力衰竭患者,RV功能障碍是运动能力差的预测指标。然而,CABG后RV功能障碍的意义、时间进程及其与运动能力的关系尚未阐明。
在这项前瞻性研究中,我们评估了CABG前后通过超声心动图三尖瓣环运动(TAM)测量的RV功能及其与运动能力的关系。
在99例接受CABG的患者中,我们在手术前进行了基线超声心动图检查,然后在CABG后3个月和1年重复进行超声心动图检查。使用在RV游离壁测量的TAM幅度评估RV功能。在CABG前后和3个月后进行运动应激试验和冠状动脉造影。
与术前测量相比,CABG后3个月通过TAM评估的RV功能显著降低(22.4对14.5mm,P<.001),1年后仍如此(14.7mm,P<.001)。CABG后3个月左心室收缩功能未改变。1年的超声心动图随访显示96%的患者出现矛盾性室间隔运动。与之前相比,CABG后3个月运动能力显著改善(1.6对1.83W/kg,P<.001)。这些发现与右冠状动脉状态无关。
与术前检查相比,CABG后1年RV功能仍然降低,室间隔运动仍然矛盾,这表明这些术后表现可能在大多数患者中是永久性的。尽管RV功能降低,但CABG后3个月的运动表现有所改善。CABG后通过TAM测量的RV功能降低可能缺乏临床意义。