Bagheri Ramin Khameneh, Ahmadi Mostafa, Alimi Hedyeh, Valaee Laya, Sahranavard Toktam, Andalibi Mohammad Sobhan Sheikh
Cardiologist, Assistant Professor, Cardiovascular Research Center, Department of Cardiology, Qaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
M.D., Resident of Cardiology, Cardiovascular Research Center, Student Research Committee, School of Medicine, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
Electron Physician. 2018 May 5;10(5):6775-6780. doi: 10.19082/6775. eCollection 2018 May.
Dobutamine stress echocardiography (DSE) is a non-invasive technique to detect coronary artery diseases (CAD). There are limited studies on evaluation of the right ventricular function by stress echocardiography. The appropriate evaluation of RV function and early diagnosis of its failure can help to improve outcomes for the patients undergoing cardiac surgery.
To determine right ventricular dysfunction in patients with three-vessel CAD by using DSE.
This cross-sectional study was among 13 patients who were candidates for coronary artery bypass grafting (CABG) referred to Ghaem Hospital, Mashhad, Iran; from September 2015 to May 2016. After a physical examination and initial measures, DSE was performed and echocardiographic parameters were recorded by a cardiologist. Paired-samples t-test was performed using SPSS Software v.16.0 for data analysis.
The study included 13 patients (9 males) with a mean age of 65.4±7.6 years. The mean of TAPS was 16.9±4.5 mm and 15.7±2.9 mm before and after stress echocardiography, respectively (p=0.69). Systolic right ventricular (SRV) peak increased from before DSE compared with after DSE (8.0±2.2 vs. 13.7±4.2 mm/s, p<0.001). In addition, after dobutamine injection, right ventricular (RV) cardiac output decreased in 7 patients and one patient was affected by post-ejection shortening.
It seems that TAPS and RV cardiac output after injection of dobutamine, can be used as markers for the recognition of ischemic RV dysfunction.
多巴酚丁胺负荷超声心动图（DSE）是一种检测冠状动脉疾病（CAD）的非侵入性技术。关于负荷超声心动图评估右心室功能的研究有限。对右心室功能进行适当评估并早期诊断其功能衰竭有助于改善心脏手术患者的预后。
通过使用DSE确定三支血管CAD患者的右心室功能障碍。
这项横断面研究纳入了2015年9月至2016年5月间转诊至伊朗马什哈德加姆医院的13例冠状动脉旁路移植术（CABG）候选患者。经过体格检查和初步测量后，进行了DSE检查，由心脏病专家记录超声心动图参数。使用SPSS软件v.16.0进行配对样本t检验以进行数据分析。
该研究包括13例患者（9例男性），平均年龄为65.4±7.6岁。负荷超声心动图前后TAPS的平均值分别为16.9±4.5mm和15.7±2.9mm（p = 0.69）。与DSE后相比，DSE前右心室收缩（SRV）峰值增加（8.0±2.2对13.7±4.2mm/s，p<0.001）。此外，注射多巴酚丁胺后，7例患者右心室（RV）心输出量下降，1例患者受射血后缩短影响。
多巴酚丁胺注射后的TAPS和RV心输出量似乎可作为识别缺血性右心室功能障碍的标志物。
