Martínez Odriozola P, Miguel de la Villa F, Solano López D, de las Heras B, Franco Vicario R, Bilbao Goitia P, García Jiménez N, Muñoz Sánchez J
Departamento de Medicina, Universidad del País Vasco, Hospital Civil, Bilbao.
Rev Clin Esp. 1992 Oct;191(5):245-51.
Cardiac function is studied with regular hemodynamic determinations and 2D-doppler echocardiography, in 22 patients with massive ascites. Patients were divided in two groups: 1. Hepatic cirrhosis (n = 12) and 2. Peritoneal carcinomatosis (n = 10). Patients with carcinomatosis showed lowered heart-beat volume, cardiac output, ventricular work and ejection fraction in comparison with cirrhotic patients. In cirrhotic patients the hemodynamic study was done before and after an evacuatory paracentesis, following which an improvement in cardiac function was shown, with significant increments in heart-beat volume, cardiac output, ventricular work, and ejection fraction. 42% of the cirrhotic patients showed an hyperdynamic circulatory status in the baseline study, but after paracentesis this hyperkinetic status was present in 100% of the patients. It is suggested that tension ascites influences negatively in cardiac function because it difficult the venous return. This depression in the ventricular function is more obvious in patients with carcinomas that in cirrhotic patients due to the fact that the former do not have a previous circulatory status.
对22例大量腹水患者通过定期进行血液动力学测定和二维多普勒超声心动图来研究心脏功能。患者分为两组:1. 肝硬化(n = 12)和2. 腹膜癌(n = 10)。与肝硬化患者相比,患有癌病的患者心搏量、心输出量、心室作功和射血分数降低。对肝硬化患者在放腹水前后进行血液动力学研究,结果显示放腹水后心脏功能有所改善,心搏量、心输出量、心室作功和射血分数显著增加。42%的肝硬化患者在基线研究中表现为高动力循环状态,但放腹水后100%的患者出现这种高动力状态。提示张力性腹水对心脏功能有负面影响,因为它阻碍静脉回流。由于癌病患者没有先前的循环状态,所以心室功能的这种抑制在癌病患者中比在肝硬化患者中更明显。