Moreu Burgos J, Fernández de Miguel J M, Ugarte Peña M, Domínguez Puente J R, Martín Júdez V
Servicio de Hemodinámica, Hospital Puerta de Hierro, Madrid.
Rev Esp Cardiol. 1992 Dec;45(10):645-51.
From October 1984 to June 1991, 1,549 endomyocardial biopsies (EMB) were performed on 122 patients submitted to a Cardiac Transplant procedure (CT) at the Hospital Puerta de Hierro in Madrid. All biopsies were performed with the long sheath technique and the King bioptome. A total of 8,707 specimens were obtained, of which 7,311 (83.97%) were considered adequate for pathological examination. We did not find significant differences between the internal jugular (83.21%) and the femoral vein (84.82%) approaches. About 20% of the samples were not adequate for pathological evaluation after the fifth procedure performed on the same patient. There has been no deaths in our group. One patient (0.06%) had right ventricular perforation with tamponade that required surgical treatment. Two patients (2.98%) presented coronary fistulae related to EMB. The percent of other minor complications was less than 0.5%. EMB is mandatory for the control of rejection in the first year after cardiac transplantation, and has shown to be a reliable and safe method in experienced hands.
1984年10月至1991年6月，马德里铁之门医院对122例接受心脏移植手术（CT）的患者进行了1549次心内膜心肌活检（EMB）。所有活检均采用长鞘技术和金氏活检钳进行。共获取8707份标本，其中7311份（83.97%）被认为适合病理检查。我们发现颈内静脉入路（83.21%）和股静脉入路（84.82%）之间没有显著差异。在同一患者进行第五次手术后，约20%的样本不适合病理评估。我们组没有死亡病例。1例患者（0.06%）发生右心室穿孔并伴有心包填塞，需要手术治疗。2例患者（2.98%）出现与心内膜心肌活检相关的冠状动脉瘘。其他轻微并发症的发生率低于0.5%。心内膜心肌活检对于心脏移植术后第一年的排斥反应监测是必不可少的，并且在经验丰富的医生手中已被证明是一种可靠且安全的方法。
