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[几种药物的免疫抑制活性及其对鸡白痢病抗体形成的影响]

[Immunosuppressive activity of several drugs and their effect on antibody formation in pullorum disease].

作者信息

Girginov G, Vodas K, Drumev D

出版信息

Vet Med Nauki. 1977;14(10):14-20.

PMID:147557
Abstract

Furazolidon given alone or in combination with chloramphenicol, with spectinomycin, with gentamycin or with sodium arsenilate as well as chlorpyrazine, applied alone, suppress the clinical manifestation of pullorum disease in birds both in the experimental and in the spontaneous outbreak of the disease. These medicinal drugs lower the production of agglutinins in birds--mostly the combination furazolidon+chloramphenicol, followed by furazolidon+sodium arsenilate. The same combinations do not prove essentially effective in influencing the development of the morphologic lesions and do not fully exempt the body from the causative agent of pullorum disease.

摘要

单独使用呋喃唑酮,或与氯霉素、壮观霉素、庆大霉素、对氨基苯胂酸钠联合使用,以及单独使用氯吡嗪,在实验性和自然爆发的禽白痢疾病中,均能抑制禽类白痢病的临床表现。这些药物会降低禽类凝集素的产生——主要是呋喃唑酮+氯霉素组合,其次是呋喃唑酮+对氨基苯胂酸钠组合。同样的组合在影响形态学病变发展方面并未显示出本质上的有效性,也不能使机体完全摆脱禽白痢病病原体。

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