Isomäki H
Rheumatism Foundation Hospital, Heinola, Finland.
Scand J Rheumatol Suppl. 1992;95:3-8. doi: 10.3109/03009749209101477.
Although developments in surgical and medical treatment methods have improved the average long-term outcome of rheumatoid arthritis (RA), it still is a severe disease. An 8-year follow-up study of patients with seropositive RA showed a large variation in the outcome. Only 24 percent of patients had no progression in the radiological destruction of the joints of hands and feet. Premature mortality seems to accumulate in patients with a poor outcome. Study of prognostic markers for RA would be of great importance.
尽管手术和药物治疗方法的发展改善了类风湿性关节炎（RA）的平均长期预后，但它仍然是一种严重的疾病。一项对血清阳性RA患者的8年随访研究显示，预后存在很大差异。只有24%的患者手足关节的放射学破坏没有进展。预后较差的患者似乎过早死亡的情况较多。对RA预后标志物的研究将非常重要。
