肿瘤标志物与结直肠癌：在管理中的应用

Tumor markers and colorectal cancer: utility in management.

作者信息

Crawford Nigel P S, Colliver Daniel W, Galandiuk Susan

机构信息

Price Institute of Surgical Research, Department of Surgery, University of Louisville, Kentucky 40292, USA.

出版信息

J Surg Oncol. 2003 Dec;84(4):239-48. doi: 10.1002/jso.10325.

DOI:10.1002/jso.10325

PMID:14756436

Abstract

Colorectal cancer (CRC) is a leading cause of morbidity and mortality. Although genetic testing can screen for rare hereditary CRC syndromes, there is no ideal means of screening for sporadic forms of CRC. This review will focus on markers that are currently used in the management of sporadic CRC and their limitations, as well as possible future clinical applications.

摘要

结直肠癌（CRC）是发病和死亡的主要原因。尽管基因检测可筛查罕见的遗传性结直肠癌综合征，但尚无理想的方法来筛查散发性结直肠癌。本综述将聚焦于目前用于散发性结直肠癌管理的标志物及其局限性，以及未来可能的临床应用。