Koelz H R, Blum A L
Medizinische Klinik, Stadtspital Triemli, Zürich.
Ther Umsch. 1992 Nov;49(11):749-60.
Medical treatment of acute ulcers can be optimized by paying attention to risk factors for slow healing and for rapid recurrence. Therapy-resistant ulcers have become virtually unknown with modern drugs, so elective ulcer surgery is nowadays rarely needed for this reason. While drug therapy of acute ulcer hemorrhage is probably of little, if any, benefit for stopping bleeding, endoscopic treatment reduces the risk of continuous or recurrent bleeding, the need for emergency surgery, and mortality of this most common complication.
通过关注溃疡愈合缓慢和快速复发的风险因素,可以优化急性溃疡的药物治疗。现代药物已使治疗抵抗性溃疡几乎绝迹,因此如今很少因这一原因而需要进行选择性溃疡手术。虽然急性溃疡出血的药物治疗对止血可能益处不大(即便有也微乎其微),但内镜治疗可降低持续出血或再出血的风险、急诊手术的必要性以及这种最常见并发症的死亡率。