Tubbs R Shane, Wellons John C, Iskandar Bermans J, Oakes W Jerry
Department of Cell Biology, University of Alabama at Birmingham, USA.
J Neurosurg. 2004 Feb;100(2 Suppl Pediatrics):86-9. doi: 10.3171/ped.2004.100.2.0086.
Historically, cutaneous stigmata representative of occult spinal dysraphism (OSD) have included lumbar hemangiomas. Frequently, this skin change is found in conjunction with other cutaneous alterations such as dermal sinus tracts and subcutaneous lipomas. Debate has recently surrounded the question of whether these skin changes in isolation might indicate underlying spinal disease. The authors reviewed their experience in their most recent 120 cases in which OSD was diagnosed.
The authors retrospectively reviewed records obtained in 120 patients with OSD. They found that many of the patients reviewed harbored only a flat capillary hemangioma as an indicator of OSD. In 21 patients (17.5%) with only midline lumbosacral flat capillary hemangiomas, underlying OSD was present. No single variety of OSD had a higher incidence of association with this single cutaneous stigma.
Based on their experience, the authors recommend magnetic resonance (MR) imaging evaluation in cases involving this skin lesion in isolation to discern the potential for surgically significant spinal cord anomalies. Prospective studies are now needed to examine MR images obtained in all children with this lesion in the midline lumbosacral spine and assess for OSD.
从历史上看,隐匿性脊柱裂(OSD)的皮肤特征包括腰部血管瘤。通常,这种皮肤变化常与其他皮肤改变同时出现,如皮样窦道和皮下脂肪瘤。最近,关于这些孤立的皮肤变化是否可能提示潜在的脊柱疾病存在争议。作者回顾了他们最近诊断出的120例OSD病例的经验。
作者回顾性分析了120例OSD患者的记录。他们发现,许多接受评估的患者仅患有扁平毛细血管瘤作为OSD的指标。在仅患有腰骶部中线扁平毛细血管瘤的21例患者(17.5%)中,存在潜在的OSD。没有单一类型的OSD与这种单一皮肤特征的关联发生率更高。
基于他们的经验,作者建议对孤立出现这种皮肤病变的病例进行磁共振(MR)成像评估,以识别具有手术意义的脊髓异常的可能性。现在需要进行前瞻性研究,检查所有腰骶部中线有此病变的儿童的MR图像,并评估是否存在OSD。