经颞叶切除术治疗的下丘脑节细胞胶质瘤。病例报告及文献复习。

Hypothalamic ganglioglioma treated by temporal lobectomy. Case report and review of the literature.

作者信息

Aryan Henry E, Meltzer Hal S, Levy Michael L, Szkandera Bartek J, Bruce Derek A

机构信息

Division of Neurosurgery, University of California, San Diego, San Diego Medical Center, 92103-8893, USA.

出版信息

J Neurosurg. 2004 Feb;100(2 Suppl Pediatrics):217-9. doi: 10.3171/ped.2004.100.2.0217.

DOI:10.3171/ped.2004.100.2.0217

PMID:14758954

Abstract

The authors report the case of a hypothalamic ganglioglioma with left-sided temporal lobe extension in an 8-year-old girl who presented with seizures. Other cases of ganglioglioma involving the hypothalamus have been reported in the literature; however, this site of origin is exceedingly rare and worthy of report. Treatment involved medial temporal lobectomy with the hypothalamic component of the tumor remaining untouched. The patient recovered postoperatively with no neurological deficits and was seizure free at 12 months. Neither radio- nor chemotherapy was recommended because of the tumor histology, location, and the patient's age. The authors recommend follow up and surgical treatment for possible tumor recurrence. The prognosis for hypothalamic ganglioglioma is unknown.

摘要

作者报告了一名8岁患癫痫的女孩，其患有下丘脑神经节胶质瘤并向左颞叶扩展的病例。文献中已报道了其他累及下丘脑的神经节胶质瘤病例；然而，这个起源部位极其罕见，值得报告。治疗方法为颞叶内侧切除术，肿瘤的下丘脑部分未予处理。患者术后恢复良好，无神经功能缺损，术后12个月无癫痫发作。由于肿瘤的组织学、位置及患者年龄，未建议进行放疗或化疗。作者建议进行随访，并针对可能的肿瘤复发采取手术治疗。下丘脑神经节胶质瘤的预后尚不清楚。