卡培他滨诱发冠状动脉痉挛——一例报告

Capecitabine-induced coronary vasospasm--a case report.

作者信息

Rizvi Asad A, Schauer Peter, Owlia Dariush, Kallal James E

机构信息

Division of Cardiology, Department of Medicine, Hartford Hospital, Hartford, CT, USA.

出版信息

Angiology. 2004 Jan-Feb;55(1):93-7. doi: 10.1177/000331970405500114.

DOI:10.1177/000331970405500114

PMID:14759096

Abstract

The authors report the case of a 70-year-old man with metastatic colon cancer and no known history of coronary disease or major risk factors who developed coronary vasospasm after the initiation of capecitabine (Xeloda). Although coronary vasospasm has been associated with another older fluoropyrimidine compound, 5-fluorouracil, this is the first reported occurrence with this relatively newer cancer drug.

摘要

作者报告了一例70岁男性转移性结肠癌患者的病例，该患者无冠心病病史或已知主要危险因素，在开始使用卡培他滨（希罗达）后发生冠状动脉痉挛。虽然冠状动脉痉挛已与另一种较老的氟嘧啶化合物5-氟尿嘧啶相关联，但这是首次报道这种相对较新的抗癌药物引发冠状动脉痉挛的病例。