Tashchuk V K, Malinovskaia I E
Lik Sprava. 1992 Aug(8):15-8.
Along with organic involvement of the coronary arteries their spasm is one of the mechanisms of development of acute myocardial ischemia. Transesophageal electrocardiostimulation in 314 patients with non-stable stenocardia revealed in 32 (10.2%) increased vasospastic activity. Holter monitoring allowed to find essential differences in patients with vasospasm manifested in a significant increase of the frequency and duration of nonpainful myocardial ischemia in the absence of distinct changes in painful ischemia. Two-week treatment with calcium antagonists allowed to reduce the ischemia level in the group of patients with vasospasm tendencies.
除冠状动脉的器质性病变外，其痉挛也是急性心肌缺血发生发展的机制之一。对314例不稳定型心绞痛患者进行经食管心电图刺激检查，发现32例（10.2%）患者血管痉挛活性增强。动态心电图监测发现，血管痉挛患者存在显著差异，表现为无痛性心肌缺血的频率和持续时间显著增加，而疼痛性缺血无明显变化。对有血管痉挛倾向的患者进行为期两周的钙拮抗剂治疗，可降低缺血水平。
