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监测欧洲胃癌死亡率的下降情况。

Monitoring falls in gastric cancer mortality in Europe.

作者信息

Levi F, Lucchini F, Gonzalez J R, Fernandez E, Negri E, La Vecchia C

机构信息

Cancer Epidemiology Unit and Cancer Registries of Vaud and Neuchâtel, Institut universitaire de médecine sociale et préventive, Lausanne, Switzerland.

出版信息

Ann Oncol. 2004 Feb;15(2):338-45. doi: 10.1093/annonc/mdh057.

Abstract

We have considered trends in age-standardized mortality from gastric cancer in 25 individual European countries, as well as in the European Union (EU) as a whole, in six selected central-eastern European countries and in the Russian Federation over the period 1950-1999. Steady and persisting falls in rates were observed, and the fall between 1980 and 1999 was approximately 50% in the EU, 45% in eastern Europe and 40% in Russia. However, the declines were greater in Russia and eastern Europe, since rates were much higher, in absolute terms. Joinpoint regression analysis indicated that the falls were proportionally greater in the last decade for men (-3.83% per year in the EU) and in the last 25 years for women (-3.67% per year in the EU) than in previous calendar years. Moreover, steady declines in gastric cancer mortality were observed in the middle-aged and the young population as well, suggesting that they are likely to persist in the near future. In terms of number of deaths avoided, however, the impact of the decline in gastric cancer mortality will be smaller, particularly in the EU.

摘要

我们研究了1950年至1999年期间25个欧洲国家、整个欧盟、六个选定的中东欧国家以及俄罗斯联邦胃癌年龄标准化死亡率的趋势。观察到死亡率持续稳步下降,1980年至1999年期间,欧盟下降了约50%,东欧下降了45%,俄罗斯下降了40%。然而,俄罗斯和东欧的降幅更大,因为从绝对值来看,其死亡率要高得多。连接点回归分析表明,男性在过去十年(欧盟每年下降3.83%)和女性在过去25年(欧盟每年下降3.67%)的降幅比之前历年成比例地更大。此外,中年和年轻人群的胃癌死亡率也在稳步下降,这表明在不久的将来可能会持续下降。然而,就避免死亡的数量而言,胃癌死亡率下降的影响将较小,尤其是在欧盟。

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