Baldwin Zachary K, Comerota Anthony J, Schwartz Lewis B
Section of Vascular Surgery, Department of Surgery University of Chicago, Chicago, IL, USA.
Vasc Endovascular Surg. 2004 Jan-Feb;38(1):1-9. doi: 10.1177/153857440403800101.
Venous thromboembolism (VTE) represents a significant clinical problem, affecting patients of all age groups, nationalities, and socioeconomic strata. Despite its prevalence, the paradigms for care are largely centered around primary or secondary prophylaxis, with less emphasis on actual treatment of the thrombus. With the recent rapid development of advanced endovascular techniques, it is now feasible to dissolve many thrombi using catheter-directed thrombolysis (CDT), and favorable clinical experience has been reported in over 600 patients. If performed safely, the purported benefits of CDT for DVT include a decreased incidence of persistent phlebitic symptoms, improved quality of life and, possibly, a decreased incidence of recurrent thrombotic events.
静脉血栓栓塞症（VTE）是一个重大的临床问题，影响着所有年龄组、国籍和社会经济阶层的患者。尽管其发病率很高，但护理模式主要集中在一级或二级预防，而对血栓的实际治疗关注较少。随着先进血管内技术最近的快速发展，现在使用导管定向溶栓术（CDT）溶解许多血栓是可行的，并且已有超过600例患者报告了良好的临床经验。如果安全实施，CDT治疗深静脉血栓形成（DVT）的所谓益处包括持续静脉炎症状的发生率降低、生活质量改善，以及可能降低复发性血栓形成事件的发生率。
