Swain Timothy W, Calligaro Keith D, Dougherty Matthew D
Lankenau Hospital, Wynnewood, PA, USA.
Vasc Endovascular Surg. 2004 Jan-Feb;38(1):75-82. doi: 10.1177/153857440403800110.
The management of infected prosthetic grafts is one of the most challenging problems facing vascular surgeons. High mortality and morbidity rates with traditional treatment have led many surgeons to consider different and novel strategies. Diagnosis is usually straightforward, but occasionally is unclear even after extensive clinical and radiologic investigations. Although routine total graft excision for all infected aortic grafts is still favored by some vascular surgeons, most favor only partial graft excision if only the distal limb of the graft is involved. Placement of in situ autologous vein or cryopreserved grafts have gained popularity, and investigations are continuing regarding the use of in situ antibiotic and silver-coated prosthetic grafts. In this article the authors review the incidence and etiology of aortic graft infections, methods to prevent these complications, the diagnosis of infected aortic grafts, and lastly the management of these complicated cases, including total graft excision and partial and complete graft preservation.
感染性人工血管的处理是血管外科医生面临的最具挑战性的问题之一。传统治疗方法导致的高死亡率和高发病率促使许多外科医生考虑采用不同的新颖策略。诊断通常较为直接,但即使经过广泛的临床和影像学检查,偶尔也会不明确。尽管一些血管外科医生仍然倾向于对所有感染的主动脉人工血管进行常规的全部人工血管切除,但如果仅人工血管的远端部分受累,大多数人更倾向于仅进行部分人工血管切除。原位自体静脉或冷冻保存人工血管的置入已越来越普遍,关于原位抗生素和银涂层人工血管的应用研究也在持续进行。在本文中,作者回顾了主动脉人工血管感染的发生率和病因、预防这些并发症的方法、感染性主动脉人工血管的诊断,最后是这些复杂病例的处理,包括全部人工血管切除以及部分和完全人工血管保留。