Pasqualotto Fabio Firmbach, Pasqualotto Eleonora Bedin, Agarwal Ashok, Thomas Anthony Joseph
Urological Institute, Center for Advanced Research in Human Reproduction and Infertility, Cleveland, USA.
Rev Hosp Clin Fac Med Sao Paulo. 2003 Nov-Dec;58(6):305-9. doi: 10.1590/s0041-87812003000600003. Epub 2004 Jan 28.
The incidence of vasal injury during inguinal herniorrhaphy is estimated at 0.5%. We sought to assess the patency rates and long-term fertility outcome after microsurgical repair of vasal obstruction related to prior inguinal herniorrhaphy.
Twenty procedures were performed on 13 men diagnosed with infertility and vasal injury secondary to previous inguinal herniorrhaphy. Eight of these men had undergone bilateral and 5 unilateral inguinal herniorrhaphy. Twelve procedures were vasovasostomies, 3 were crossover vasovasostomies, 2 were vasoepididymostomies, and 3 were crossover vasoepididymostomies. Eight patients were azoospermic, 2 were severely oligospermic (<1 M/mL), 1 was oligospermic, and 2 were asthenospermic. Patency data was obtained on all 13 patients, and pregnancy data was available for 10 couples (77%), with a mean follow-up of 69.5 months.
The overall patency rate was 65%. In the vasovasostomy group, the patency rate was 60% (9/15), and in the vasoepididymostomy group it was 80% (4/5). Among the azoospermic patients, 13 procedures were performed. The patency rate was 42.9% for the vasovasostomy (3/7), and 100% for the vasoepididymostomy procedure (4/4). The overall pregnancy rate was 40%. Of the men who underwent vasoepididymostomy, 80% (4/5) established a pregnancy.
Microsurgical vasovasostomy after inguinal vas injury results in a reasonable patency rate but a lower pregnancy rate than that after vasectomy reversal. When microsurgical vasoepididymostomy was possible, it resulted in high patency and pregnancy rate. Crossover vasoepididymostomy, when appropriate, can be a useful alternative to inguinal vasovasostomy.
腹股沟疝修补术中输精管损伤的发生率估计为0.5%。我们试图评估与既往腹股沟疝修补术相关的输精管梗阻显微外科修复后的通畅率和长期生育结局。
对13例诊断为不育且因既往腹股沟疝修补术导致输精管损伤的男性进行了20例手术。其中8例男性接受了双侧腹股沟疝修补术,5例接受了单侧腹股沟疝修补术。12例手术为输精管吻合术,3例为交叉输精管吻合术,2例为输精管附睾吻合术,3例为交叉输精管附睾吻合术。8例患者无精子症,2例严重少精子症(<100万/mL),1例少精子症,2例弱精子症。获得了所有13例患者的通畅数据,10对夫妇(77%)有妊娠数据,平均随访69.5个月。
总体通畅率为65%。在输精管吻合术组,通畅率为60%(9/15),在输精管附睾吻合术组为80%(4/5)。在无精子症患者中,进行了13例手术。输精管吻合术的通畅率为42.9%(3/7),输精管附睾吻合术为100%(4/4)。总体妊娠率为40%。接受输精管附睾吻合术的男性中,80%(4/5)成功妊娠。
腹股沟输精管损伤后显微外科输精管吻合术可获得合理的通畅率,但妊娠率低于输精管复通术后。当可行显微外科输精管附睾吻合术时,可获得较高的通畅率和妊娠率。适当情况下,交叉输精管附睾吻合术可作为腹股沟输精管吻合术的有用替代方法。