Hofer E, Düchler M, Fuad S A, Houchins J P, Yabe T, Bach F H
Laboratory of Transplantation Immunology, Vienna International Research Cooperation Center, Austria.
Immunol Today. 1992 Nov;13(11):429-30. doi: 10.1016/0167-5699(92)90067-H.
Among the high points of immunological discovery has been the identification of antigen-recognizing receptors on B and T cells. Of the lymphocyte populations, only the NK cell receptor remains unknown. Consequently, any newly-recognized, cell-surface molecules expressed selectively on NK cells, especially ones that can transmit a signal to the cell upon appropriate ligand interaction, are possible candidates. This article describes such candidates.
免疫学发现的重要成果之一是鉴定出了B细胞和T细胞上的抗原识别受体。在淋巴细胞群体中,只有自然杀伤(NK)细胞受体仍然未知。因此,任何新发现的、在NK细胞上选择性表达的细胞表面分子,尤其是那些在与适当配体相互作用时能向细胞传递信号的分子,都有可能是候选分子。本文介绍了这类候选分子。